Molecular Knowledge Systems provides a variety of educational resources to help you better utilize our software products, understand physical property estimation and design new chemical products. We provide courses, webinars, presentations, white papers and more. Many of these resources are available for free from the links on this page. Please contact us for information about our instructor led courses.
01) Basic and Common Operations
(pdf download)
This presentation details the terms and operations that are
repeatedly used throughout Cranium and Synapse.
02) Editing Molecular Structure
(pdf download)
This presentation details the use of Cranium's and Synapse's
structure editor to enter the structure of molecules
and groups.
03) Estimating Chemical Properties
(video)
Demonstration of Cranium's and Synapse's capabilities for
estimating the physical properties of pure chemicals.
04) Estimating Mixture Properties
(video)
Demonstration of Cranium's and Synapse's capabilities
for estimating the physical properties of mixtures.
05) Editing and Adding Estimation Techniques
(video)
Demonstration of the procedures
for editing existing estimation techniques or adding new
estimation techniques. Applicable to both Cranium and
Synapse.
06) Estimating Vapor-Liquid Equilibria
(video)
Demonstrates the use of Cranium and Synapse
for estimating bubble and dew points.
07) Designing Chemicals
(video)
Details the basic steps needed to use Synapse to design a
new chemical which satisfies a set of physical property
and molecular structure constraints.
The table to the right lists a variety of knowledge bases and documents. Some of these are updated versions of those documents distributed with Cranium and Synapse. Others are specialty documents that focus on particular types of chemicals or applications.
MKS Core Knowledge Base
This knowledge base contains
physical property data for more than 950
chemicals, 300 mixtures and 190 estimation techniques.
MKS TGER Template Knowledge Base
This knowledge base is often used as the starting document for a new
knowledge base. The MKS TGER Template KB contains information on
techniques (T), groups (G), elements (E) and references (R). No
chemical or mixture entities are contained within this
knowledge base.
MKS GER Template Knowledge Base
This knowledge base is often used for importing physical property
values and technique parameters from the files of other software
programs, e.g., process simulation document files. The MKS
GER Template KB contains information on groups (G),
elements (E) and references (R). No chemical, mixture or
technique entities are contained within this knowledge base.
MKS Sample Knowledge Base
This knowledge base is often used for learning and experimentation
purposes. It contains approximately 400 chemicals, 100 mixtures
and 200 estimation techniques. Because the Sample KB is smaller
than the Core KB, it is often quicker to use the Sample KB
when using the Reader versions of Cranium and Synapse.
MKS Organosilicon Evaluation KB
This knowledge base is contains physical property data for 65
organosilicon chemicals. Some of these data are not included in
the MKS Core Knowledge Base. The data in this knowledge base
was used to evaluate the accuracy and applicability of
Cranium's and Synapse's estimation techniques for organosilicon
chemicals. (See
the evaluation webpage for
details.)
The case studies, evaluations, and technical notes listed in the table to the right provide extended examples of how Cranium and Synapse can be used to solve a variety of physical property problems.
Using Cranium to Find Azeotropes
This case study shows how to use
Cranium or Synapse to find binary azeotropes. It
contains a technical paper explaining the thermodynamic basis of the
methodology, a video showing all the steps needed to search for
azeotropes, a
bookmarks document containing a list of common solvents and a
knowledge base containing the needed data and estimation techniques.
Estimating Properties of Organosilicon Chemicals
This evaluation investigated how well Cranium and Synapse can estimate
the physical properties of organosilicon chemicals. Estimates by techniques
for the normal boiling point, critical temperature, critical pressure,
liquid density, and liquid vapor pressure were compared against
experimental data.
A variety of online resources, software downloads and online documents are listed in the table to the right.
MKS YouTube Channel
A compilation of
additional instructional videos on physical property estimation and the
operation of Cranium and Synapse.
MKS LinkedIn Physical Property Estimation Group
Join our LinkedIn group for discussions on physical property
estimation and other topics related to physical properties.
MKS Facebook Page
Follow us on our Facebook page to keep updated
on our activities and new software developments.
Online Property Estimation
This webpage enables you to estimate several physical properties of
pure chemicals using group contribution
and equation oriented estimation techniques. It is a very good
place to become familiar
with physical property estimation.
Manually Installing License Key Software
The license key (Sentinel HASP by Gemalto) that comes with our software products should automatically
install any needed software when it is first inserted into your computer.
If the software is not successfully installed then please try removing the key, rebooting your
computer and reinserting the license key before you start any other program. The following file contains the
latest license key installation program and software:
Drivers Installer.